Metronidazole extended-release tablets are usually taken once daily at least 1 hour before or 2 hours after a meal for 7 days. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take metronidazole exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. Swallow. Retrouvez sur VIDAL la liste des médicaments contenant la substance active Métronidazole : BI MISSILOR, BIRODOGYL Metronidazole concentrations in milk were 7.3, 9.6 and 10.1 mg/L.[13] Infant Levels. Ten 5-day-old infants were breastfed every 4 hours after a single 200 mg oral dose of metronidazole was given to their mothers. Two infants had metronidazole serum levels of 0.28 and 0.4 mg/L and 3 had unmeasurable ( 0.05 mg/L) levels 8 hours after the dose. Pustulose Exanthématique Aigüe Généralisée (PEAG) ont été rapportés avec le metronidazole. Les patients doivent être informés des signes et symptomes et une surveillance cutanée rapprochée doit être pratiquée. La survenue de signes ou symptomes de Syndrome de Stevens-Jonhson, Syndrome de Lyell (ex : éruption progressive souvent accompagnée de bulles ou de lésions des muqueuses.